Addressing an ageing population: report highlights coffee’s potential role in reducing cognitive decline

Symposium at the European Union Geriatric Medication Society Congress 2016 discusses the role of nutrition in cognitive function as we age

28 November 2016 A new report from the Institute for Scientific Info on Coffee (ISIC), a not-for-profit organisation devoted to the research and disclosure of science relevant to coffee and overall health, highlights the potential role of coffee consumption in reducing the chance of cognitive decline. The report concludes that a reasonable intake of coffee (three-five cups per day) could provide safety towards age-connected cognitive decline and other neurodegenerative ailments such as Alzheimer’s and Parkinson’s.

The report provides a summary of the investigation presented at ISIC’s symposium, titled ‘Nutrition, Coffee and Age-Connected Cognitive Decline’, held in the course of the European Union Geriatric Medication Society’s 2016 Congress in Lisbon, Portugal. The findings are specifically relevant given Europe’s ageing population: the amount of individuals aged 60 years or in excess of is projected to rise to 217.2 million by 2030one, for that reason knowing and communicating diet regime and life-style aspects that may possibly restrict age-connected cognitive decline will help to improve the good quality of lifestyle for this expanding demographic.

The symposium speakers whose insights and analysis contributed to ISIC’s report were:

  • Professor Lisette de Groot, Professor of Nutrition and Ageing, Division of Human Nutrition at Wageningen University (The Netherlands)
  • Professor Rodrigo A. Cunha, Professor at the Faculty of Medicine of the University of Coimbra and Principal Investigator at the Centre for Neuroscience and Cell Biology of the University of Coimbra (CNC) (Portugal)
  • Dr Elisabet Rothenberg, Associate Professor of Nutrition at Kristianstad University (Sweden)

Important highlights about coffee from the report incorporate:

  • Investigation published in 2016 suggests that moderate coffee consumption can minimize the danger of building Alzheimer’s by up to 27%two. Investigation has recommended that it is typical, lengthy-term coffee drinking that is crucial to helping to lessen the risk of Alzheimer’s Conditionthree.
  • The association among coffee consumption and cognitive decline is illustrated by a ‘U-shaped’ pattern in latest meta-analyses, with the greatest protection observed at an intake of roughly three-five cups of coffee per dayfour.
  • Although the exact mechanisms of action behind the advised association amongst coffee and age-relevant cognitive decline are unknown, caffeine is likely to be concerned. There are several other compounds in coffee, such as antioxidants and anti-inflammatory agents, which may possibly also perform a function. Caffeic acid, for instance, is a polyphenol (antioxidant) located in coffee, and study suggests that these may possibly be related with improved cognitive function5.

Professor Rodrigo A. Cunha, Professor at the Faculty of Medicine of the University of Coimbra and Principal Investigator at the Centre for Neuroscience and Cell Biology of the University of Coimbra (CNC), Portugal, commented:

“Healthcare pros have an important element to perform in supplying individuals with exact investigation-primarily based information, to aid them to adhere to a healthy diet program and life-style, and in flip, lessen their risk of age-related cognitive decline. Reasonable coffee consumption could perform a considerable role in decreasing cognitive decline which would influence wellness outcomes and healthcare spending across Europe.”

In its Scientific View on the security of caffeine, the European Meals Safety Authority (EFSA) concluded that intakes of up to 400mg of caffeine (the equivalent of up to five cups of coffee per day), from all sources, do not raise any concerns for healthy adults6. A single cup of coffee gives approximately 75-100mg caffeine.

To go through the report, please click right here.



  1. The Department of Financial and Social Affairs of the United Nations Secretariat, ‘World Population Ageing Report 2015’. Available at:
  2. Liu Q.P. et al. (2016) Habitual coffee consumption and danger of cognitive decline/dementia: A systematic assessment and meta-examination of prospective cohort studies. Nutr, 32(6):628-36.
  3. Cao C. et al. (2012) Higher blood caffeine ranges in MCI linked to lack of progression to dementia. J Alzheimers Dis, 30(three):559-72.
  1. Van Gelder B.M. et al. (2007) Coffee consumption is inversely linked with cognitive decline in elderly European guys: the FINE Study. Eur J Clin Nutr, 61(two):226-32.
  2. Khan K.A. et al. (2013) Influence of caffeic acid on aluminium chloride-induced dementia in rats. Journal of Pharmacy and Pharmacology, 65(12):1745-1752.
  3. EFSA (2015) Scientific Viewpoint on the Safety of Caffeine. EFSA Journal, 13(five):4102.

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